Search results for "N ligand"

showing 10 items of 46 documents

Phosphasalen group IV metal complexes: synthesis, characterization and ring opening polymerization of lactide.

2020

International audience; We report the synthesis of a series of Zr and Ti complexes bearing phosphasalen which differs from salen by the incorporation of two P atoms in the ligand backbone. The reaction of phosphasalen proligands (1a-1c)H2 with Zr(CH2Ph)4 led to different products depending on the nature of the N,N-linker in the ligand. In case of ethylene-linked phosphasalen, octahedral Zr complex 2a formed as a single stereoisomer in trans geometry. With the phenylene linker, it was shown by dynamic NMR spectroscopy that complex 2b exists as a mixture of trans and cis-β isomers in solution, both enantiomers (Δ and Λ) of the cis-β isomer being in fast equilibrium with respect to the NMR tim…

010402 general chemistryLIGANDS SYNTHESIS01 natural sciencesRing-opening polymerizationCoordination complexInorganic ChemistryINDIUM COMPLEXESOctahedral molecular geometry[CHIM]Chemical SciencesSALALEN COMPLEXESCYCLIC ESTERSCOORDINATION CHEMISTRYZIRCONIUM COMPLEXES; COORDINATION CHEMISTRY; SALALEN COMPLEXES; LIGANDS SYNTHESIS; INDIUM COMPLEXES; SALEN LIGANDS; CYCLIC ESTERS; INITIATORS; CATALYSIS; ALUMINUMchemistry.chemical_classification010405 organic chemistryLigandCATALYSISCationic polymerizationNuclear magnetic resonance spectroscopyALUMINUM0104 chemical sciencesCrystallographychemistrySALEN LIGANDSAlkoxy groupINITIATORS[CHIM.OTHE]Chemical Sciences/OtherIsomerizationZIRCONIUM COMPLEXESDalton transactions (Cambridge, England : 2003)
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The [Pd(bipy)]2+ “merry-go-round”: Insights into the lability of the Pd–N bond

2009

Abstract Two tripods (1 and 2) featuring pyrimidinyl pendant arms have been synthesized from 5-(1H-pyrazol-3-yl)-pyrimidine (5) and 1,3,5-tribromomethylbenzene derivatives. Reaction with three equivalents of [Pd(bipy)](NO3)2 to form a macrotricycle closed by palladium coordination unexpectedly afforded the mononuclear species [Pd(1)(bipy)]2+ and [Pd(2)(bipy)]2+. These complexes show fluxional behavior on the 1H NMR timescale, the [Pd(bipy)]2+ fragment hopping between the pyrimidinyl coordinating moieties. The ΔGc‡’s estimated by the coalescence method are temperature independent, which means that ΔSc‡ = 0. This indicates that the “merry-go-round” process of [Pd(bipy)]2+ occurs intramolecula…

010405 organic chemistryStereochemistryChemistryLabilityGeneral Chemical Engineeringfluxionality[ CHIM.COOR ] Chemical Sciences/Coordination chemistryTemperature independentchemistry.chemical_elementGeneral Chemistry010402 general chemistrypalladium01 natural sciencesMedicinal chemistry0104 chemical scienceschelatesN ligandsNucleophileProton NMRChelation[CHIM.COOR]Chemical Sciences/Coordination chemistryComputingMilieux_MISCELLANEOUStripodal ligandsPalladium
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Binding mode analysis of ABCA7 for the prediction of novel Alzheimer's disease therapeutics

2021

Graphical abstract

ATP Adenosine-triphosphateNBD nucleotide binding domainGSH reduced glutathionePolypharmacologyAlzheimer’s disease (AD)ATP-binding cassette transporterHTS high-throughput screeningBiochemistryABCA7Structural BiologyPLIF protein ligand interactionMSD membrane spanning domainPDB protein data bankTM transmembrane helixABC ATP-binding cassetteMultitarget modulation (PANABC)RMSD root mean square distanceABC transporter (ABCA1 ABCA4 ABCA7)Computer Science ApplicationsMOE Molecular Operating EnvironmentPharmacophoreSNP single-nucleotide polymorphismBiotechnologyResearch ArticleBBB blood-brain barrierBiophysicsDrug designComputational biologyBiologyAD Alzheimer’s diseasePET positron emission tomographyIC intracellular helixAPP amyloid precursor proteincryo-EM cryogenic-electron microscopyGeneticsHomology modelingBinding siteRational drug design and developmentComputingMethodologies_COMPUTERGRAPHICSNBD-cholesterol 7-nitro-2-13-benzoxadiazol-4-yl-cholesterolTransporterPSO particle swarm optimizationPET tracer (PETABC)ECD extracellular domainR-domain/region regulatory domain/regionABCA1biology.proteinEH extracellular helixTP248.13-248.65BODIPY-cholesterol 44-difluoro-4-bora-3a4a-diaza-s-indacene-cholesterolComputational and Structural Biotechnology Journal
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Input of P, N-(phosphanyl, amino)-ferrocene hybrid derivatives in late transition metals catalysis

2018

International audience; Unequally functionalized ferrocenes give access to valuable hemilabile reactivity in catalytic reaction. We address the synthesis of hybrid (P, N)-ferrocenyl compounds for which recent catalytic breakthrough applications have been reported, transversely in late transition metals chemistry. Palladium, nickel, rhodium, iridium, and emerging iron and gold catalysis are illustrated from selected examples, which include CC bond formation from cross-coupling and polymerization, allylic substitution, cyanation, hydroformylation, CH arylation and silylation and hydrogenation reactions.

Allylic rearrangementnickel-complexesAminophosphinesethylene oligomerizationchemistry.chemical_elementHomogeneous catalysispbeta-ketoestersCyanation[CHIM.INOR]Chemical Sciences/Inorganic chemistry010402 general chemistryn ligands01 natural sciencesRhodiumCatalysisInorganic ChemistryPolymer chemistryoxazoline-containing ligandsMaterials ChemistryOrganic chemistry[CHIM]Chemical SciencesReactivity (chemistry)Physical and Theoretical ChemistryPolyfunctionalized ligandsferrocenyl ligands010405 organic chemistryasymmetric catalysisHemilabile hybridsHomogeneous catalysischiral ligandssimple ketones0104 chemical scienceschemistrystructural-characterizationFerroceneHydroformylationPalladiumLate transition metals
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Photoinduced HS state in the first spin-crossover chain containing a cyanocarbanion as bridging ligand

2009

A new polymeric approach, based on cyanocarbanion ligands, for the design of spin crossover (SCO) compounds led us to the compound [Fe(abpt)2(tcpd)] (1) (tcpd^2 = (C[C(CN)2|3)^2 , abpt = 4-amino-3,5-bis(pyridin-2-yl)-1,2,4-triazole) which has been characterised as the first SCO molecular chain involving a cyanocarbanion as bridging ligand. Gomez Garcia, Carlos Jose, Carlos.Gomez@uv.es

Cyanocarbanion ligandsChemistryStereochemistryUNESCO::QUÍMICAPolimeryc approachMetals and AlloysBridging ligandBridging ligandGeneral ChemistryState (functional analysis)UNESCO::QUÍMICA::Química macromolecular:QUÍMICA [UNESCO]CatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsChain (algebraic topology)Polimeryc approach ; Cyanocarbanion ligands ; Photoinduction ; Bridging ligandSpin crossoverPhotoinductionMaterials ChemistryCeramics and Composites:QUÍMICA::Química macromolecular [UNESCO]
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Ruthenium Metallodendrimers Based on Nitrile‐Functionalized Poly(alkylidene imine)s

2005

The preparation of the first- and second-generation of nitrile-functionalized poly(alkylidene imine) dendrimers with the organometallic ruthenium complex [Ru(η5-C5H5)(PPh3)2Cl] peripherally attached is described. The reaction of N,N′-bis(cyanomethyl)piperazine (1), N,N′-bis[N′′,N′′′-bis(cyanoethyl)aminoethyl]piperazine (2), or N,N,N′,N′-tetrakis(cyanoethyl)ethylenediamine (3) with [Ru(η5-C5H5)(PPh3)2Cl] (4) in the presence of TlPF6 gives the new air-stable ruthenium metallodendrimers 5, 6, and 7, respectively. These stable metallodendrimers are easily prepared and represent a novel quantitative method to solidify and chromatographically purify the otherwise semi-liquid nitrile-functionalize…

DendrimersNitrileIminechemistry.chemical_elementEthylenediamineSandwich complexes.Mass spectrometryRutheniumRutheniumInorganic ChemistryFaculdade de Ciências Exatas e da Engenhariachemistry.chemical_compoundPiperazineN ligandschemistryDendrimerPolymer chemistryOrganic chemistry31p nmr spectroscopyEuropean Journal of Inorganic Chemistry
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Preparation and Characterization of Novel Poly(alkylidenamine) Nitrile Ruthenium Metallodendrimers

2010

Complete functionalization of N,N,N',N'-[tetrakis(cyanoethyl)-hexamethylenediamine] [N≡C(CH 2 ) 2 ] 2 N(CH 2 ) 6 N[(CH 2 ) 2 -C≡N] 2 (4) and N,N,N',N'-(tetrakis(cyanoethoxypropyl)hexamethylenediamine] [N≡C(CH 2 ) 2 O(CH 2 ) 3 ] 2 N(CH 2 ) 6 N[(CH 2 ) 3 -O(CH 2 ) 2 C≡N] 2 (7) with the organometallic moiety [Ru(η 5 -C 5 H 5 )(PPh 3 ) 2 Cl] and the five-coordinate cis-[RuCl(dppe) 2 ]-[PF 6 ] [dppe = 1,2-bis(diphenylphosphanyl)ethane] was attained with good yield, respectively, by treating the metallo-fragment with the core in methanol (at room temperature and in presence of TIPF 6 as a chloride abstractor) and in 1,2-dichloroethane (under reflux). These novel nitrile-functionalized poly(alkyli…

DendrimersPolynuclear complexesNitrileStereochemistrychemistry.chemical_elementMetallodendrimerSandwich complexes.Medicinal chemistryRutheniumRutheniumInorganic ChemistryFaculdade de Ciências Exatas e da Engenhariachemistry.chemical_compoundN ligandschemistryHexamethylenediamineDendrimerYield (chemistry)MoietyMethanolEuropean Journal of Inorganic Chemistry
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Synthetic, structural and biochemical studies of polynuclear platinum(II) complexes with heterocyclic ligands.

2008

"Non-classical" di- and trinuclear Pt(II) complexes with polydentate nitrogen ligands; ionic [(PtCl(2))(2)(tptz)(2)(mu-PtClNCPh)]Cl (1) [tptz =2,4,6-tris(2-pyridyl)-1,3,5-triazine], [(PtCl(2))(2)(bptz)(2)(mu-Pt)]Cl(2) (2) [bptz = 3,6-bis(2-pyridyl)-1,2,4,5-tetrazine] and neutral [(PtCl(2))(2)(tptz)(2)(mu-PtCl(2))](H(2)O)(4) (3), [(PtCl(2))(2)(mu-tppz)](CHCl(3)) (4) [tppz = 2,3,5,6-tetra(2-pyridyl)pyrazine] complexes, have been prepared and structurally characterized. The neutral tptz and tppz complexes present three and two separate PtCl(2) moieties, respectively, in a cis position, presumably acting in a bifunctional mode towards DNA; the cationic tptz and bptz complexes contain monofuncti…

DenticityMagnetic Resonance SpectroscopyPyrazineSpectrophotometry InfraredStereochemistryCell SurvivalCytotoxicitychemistry.chemical_elementPlatinum CompoundsLigandsChemical synthesisPolydentate nitrogen ligandchemistry.chemical_compoundHeterocyclic CompoundsCell Line TumorDrug DiscoveryHumansBifunctionalPharmacologyMolecular StructureLigandOrganic ChemistryCationic polymerizationBiological activityGeneral MedicinechemistryPolynuclear platinum complexeSettore CHIM/03 - Chimica Generale E InorganicaPlatinumEuropean journal of medicinal chemistry
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Mono- and Binuclear Copper(II) and Nickel(II) Complexes with the 3,6-Bis(picolylamino)-1,2,4,5-Tetrazine Ligand

2021

Four new compounds of formulas [Cu(hfac)2(L)] (1), [Ni(hfac)2(L)] (2), [{Cu(hfac)2}2(µ-L)]·2CH3OH (3) and [{Ni(hfac)2}2(µ-L)]·2CH3CN (4) [Hhfac = hexafluoroacetylacetone and L = 3,6-bis(picolylamino)-1,2,4,5-tetrazine] have been prepared and their structures determined by X-ray diffraction on single crystals. Compounds 1 and 2 are isostructural mononuclear complexes where the metal ions [copper(II) (1) and nickel(II) (2)] are six-coordinated in distorted octahedral MN2O4 surroundings which are built by two bidentate hfac ligands plus another bidentate L molecule. This last ligand coordinates to the metal ions through the nitrogen atoms of the picolylamine fragment. Compounds 3 and 4 are cen…

DenticityMaterials science42Pharmaceutical Sciencechemistry.chemical_element5-tetrazinecrystal structure determination010402 general chemistry01 natural sciencesO.ArticleAnalytical ChemistryM.lcsh:QD241-441Julvechemistry.chemical_compoundTetrazinenickelStetsiukN 1lcsh:Organic chemistryA.Drug DiscoveryLloret[CHIM]Chemical SciencesPhysical and Theoretical ChemistryIsostructural1245-tetrazine010405 organic chemistryLigandHexafluoroacetylacetoneOrganic ChemistryMagnetic susceptibility0104 chemical sciencesNickelCrystallographyAvarvarichemistryChemistry (miscellaneous)F.Intramolecular forcecopperMolecular Medicinemagnetic propertiesnitrogen ligandsEl-Ghayoury
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A dinuclear rhodium(III) complex with the N,N′-ethylenebis(salicylideneiminato) (salen) ligand in a bridging bis-bidentate mode of coordination. Crys…

1990

In this communication we describe the synthesis and crystal structure of the complex [{Rh(η 2 -(C 6 H 4 )PPh 2 )(η 2 -P(o-ClC 6 H 4 )Ph 2 )} 2 (salen)]-(SbF 6 ) 2 , showing the bridging configuration of the salen ligand

DenticitySchiff baseStereochemistrychemistry.chemical_elementCrystal structureRhodiumInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryMetal salen complexesSalen ligandX-ray crystallographyMaterials ChemistryMoleculePhysical and Theoretical ChemistryInorganica Chimica Acta
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